Zingiber officinale (Z. officinale) is a perennial herb with 
several medicinal properties. Development of modern drugs 
from Z. officinale can be emphasized for the control of various 
diseases. The feasibility of using Z. officinale to treat parasite 
infections has received considerable interest nowadays. 
Therefore, this review focused on the anti-parasitic activity of Z. 
officinale. Method of this literature search was conducted on 
PubMed, Elsevier Scopus database and Google Scholar with no 
limitation on language or year of publication databases. Z. 
officinale was found to have a significant antihelmintic activity 
against Schistosoma mansoni, Toxocara canis, Dirofilaria 
immitis, Angiostrongylus cantonensis, Aniskis simplex, 
Hymenolepis nana and hydatid cysts either in vitro or in vivo. 
Also, it has an anti-protozoal effect against Toxoplasma gondii, 
Giardia lamblia, Trypanosoma brucei brucei and Blastocystis 
species. Additionally, it was found to have insecticidal, 
molluscicidal and anti-leech effects.