Browse published and in-press articles from all Aperito Publishing journals.
Objective: Methotrexate (MTX) is used for the treatment of inflammatory disorders but can cause liver enzyme abnormalities. Liver enzyme elevations are neither specific nor sensitive for detecting liver fibrosis. Li...
Several studies have shown that metastatic cancer cells may lie dormant in a secondary site for more than a decade, all the while retaining the ability to aggressively reemerge. Once these dormant cancer cells regrow, cancer ...
Background and Aims: In 1999, the diagnostic criteria of Autoimmune Hepatitis (AIH) have been revised by an international panel. This revised scoring system had a high diagnostic accuracy but was limited by its complexity. Subsequ...
The most cities which their inhabitants are suffering from fluorosis, located in plain regions or margins of seas. However; there are some other cities located in high and mountainous regions with high prevalen...
Unilateral anemic retinopathy is an uncommon but reversible condition. A 43-year-old female presented with right eye blurring of vision for one week duration. She also had menorrhagia for a year. Examination showed ...
Introduction Trauma represents a major cause of death in patients presenting in Emergency Department .Abdomen represents a commonly injured region which may often by missed in cases of blunt trauma particularly when compounde...
Purpose: Visceral Adipose Tissue (VAT) as a source of pro inflammatory and biological mediators is implicated in adverse cardiac structure remodeling, functional alternations, and results in Heart Failure (HF) in ce...
From 1919 to his death, Sigmund Freud was treated for a maxillary jawbone cancer by two exceptional surgeons, the Austrian, Hans Pichler, and the American, Varaztad Kazanjian. Escaping the Nazi regime, he went into exile in E...
Imaging of the inner ear structures is becoming essential nowadays as the increasing number of cases of cochlear implants being performed globally. We report here a case of a 19-year-old boy who had congenital hearing loss and was...
It is presented on the basis of fundamental laws of the evolution of energy systems in nature a hypothesis of the origin of "junk DNA". The noncoding DNA sequences originated according to her on the base of a combin...
Worldwide, 663 million people do not have access to improved drinking water supplies and 2.5 billion people lack access to improved sanitation including one billion who practice open defecation. Eighty-eight percent of deaths...
Generalised exudative retinal detachment, choroidal infarction and cortical blindness are known visual threatening conditions in patients with pre-eclampsia/eclampsia. Localised macula detachment is an uncommon ocular feature...
Langerhans Cell Histiocytosis (LCH) is a rare and variable disease process that mimics inflammatory and sometimes malignant disease. Diagnosis is challenging as it may simulate abscess, hematoma, acute dacryocystitis and neur...
Lacrimal gland abscess in a rare orbital infection. We report a case of orbital cellulitis secondary to lacrimal gland abscess due to acute dacryoadenitis in a child. Computed tomography of orbit confirmed the clinical ...
Sexually Transmitted Diseases (STDs) are caused by a large number of microorganisms mostly with Chlamydia trachomatis and Neisseria gonorrhoeae. Data concerning the frequency of STD agents is scarce in the Islamic W...
Obesity remains a leading cause of cardiovascular (CV) events and diabetes worldwide. Although there are at least two main body-size phenotypes (metabolically healthy and metabolically non-healthy) of individuals wi...
A 71-year-old woman was admitted to our hospital for treatment of cancer in the body and tail of the pancreas. After admission, she had tarry stool and esophagogastroduodenoscopy (EGD) was performed. EGD revealed ...
Musical Pairing® is a method of matching music to food using a simple mathematical formula. The pairing is accomplished by assigning a numerical value to the components of a meal and then finding a musical match of equal value...
Granulomatosis with polyangiitis (GPA) or Wegener’s granulomatosis is a systemic necrotizing vasculitis with small sized vessel involvement and granulomatous inflammation of ENT and/or Lung and/or Kidney that ...
Human urine contains many plant nutrients and its composition is found to be different according to human diet. The ammonical nitrogen and phosphate concentration of pure vegetarian diet urine sample was found to be 3...
Ankylosing Spondylitis (AS) is a chronic inflammatory systemic disease belonging to the SpondyloArthritidies with axial joint involvement and enthesitis, with or without peripheral arthritis and systemic involvement. We know ...
Sjogren’ Syndrome (SS) is a chronic autoimmune disease presenting with clinical hallmark of dry eyes, dry mouth and salivary gland swelling and histological hallmark of lymphocytic infiltration of exocrine glands.  ...
Vascular Calcification (VC) is the major contributors of Cardiovascular (CV) morbidity and mortality in patients with established Coronary Artery Disease (CAD), diabetes mellitus and Chronic Kidney Disease (CKD). Amongst several f...
Objective: To report a case of fungal keratitis caused by Fusarium species. Result: A 57 year old man presented with painful blurring of vision of his left eye. There was presence of dry corneal ulcer with irregular bo...
Behcet’s Disease (BD) is a chronic inflammatory multisystem disease belongs to the Vasculitidies with small, medium and large sized vessel involvement. This disorder is characterized by Oral aphthosis, Genital...
Today, dental pulp DNA, free from any dental pathology, constitutes a remarkable means of investigation in odontology but also in archeology. Indeed, numerous historical researches in forensic dentistry use this sci...
Objective: To report a case of neuro retinitis in ocular bartonellosis which showed good response to topical nepafenac 0.1%, a non-steroidal anti-inflammatory drug, in addition to the standard treatment of systemic ...
In the history of the patient with joint pain we have to know whether or not the joint pain is mechanical or inflammatory, acute or chronic and traumatic or non-traumatic. In the physical examination of the patient, it should be d...
Malaria presents a diagnostic challenge to laboratories especially in non-endemic malaria countries. Population movements and Travellers all contribute to presenting the laboratory with diagnostic problems for which it may have li...
Plasmacytoma is a rare malignant disease based of differentiated plasmatic B cells, which occurs also in the head and neck region. It rarely involves the mandible. The authors present an unusual evaluation of this pathology t...
Background: To examine the incidence of traumatic and overuse Musculoskeletal Injuries (MSI) in children and adolescents with diagnosed diabetes mellitus, which has been understudied. Methods: Using a population-b...
Aims: To evaluate the utility of endoscopic obliterative therapy with n-butyl-2-cyanoacrylate (a tissue adhesive) for gastric varices and to assess the incidence of serious complications. Methods: Endoscopic obliterative t...
Mesenchymal Stem Stem Cells (MSCs) could provide alternative therapeutic solutions for a number of bone and cartilage tissue diseases, playing an important role in regenerative medicine. Several sources of stem cells are curr...
Biogas production is growing nowadays due to the increasing installation of anaerobic digesters for organic waste treatment, mainly in Europe, promoted by the current environmental legislation. Depending on the final use, differen...
Ankylosing Spondylitis (AS) is a chronic inflammatory systemic disorder belonging to the SpondyloArthridies with axial joint involvement and enthesitis, with or without peripheral arthritis and systemic involvement....
Rheumatoid Arthritis (RA) as a chronic progressive systemic autoimmune disease with hallmark of chronic erosive polyarthritis is the most common inflammatory articular disorder. Its overall prevalence is 1% and it is more common i...
Osteochondroma or bony exostosis is a common benign tumor of bone occurring predominantly in long bones. It may arise infrequently from the spine giving rise to vague symptoms as backache or may lead to compressive myelopathy due ...
The recognition of the importance of overweigh / obesity and metabolic syndrome as leading risk factor for diabetes and cardiovascular (CV) complications has greatly increased within last decades. Endothelial dysfunction mediating...
Diabetes Mellitus (DM) is a global health problem and increasing all over the world at an alarming rate that appears dramatic as to have been characterized as an epidemic. DM is a chronic metabolic and hormonal disorder and i...
Astrocytes are glial cells that play a crucial role in providing a supportive environment for neurons, mainly by cell. cell interactions mediating numerous physiological and biochemical functions in the central nervous system (CNS...
Giant Cell Arteritis (GCA) is a systemic vasculitis involving medium to large sized vessels most commonly the cranial branches of the arteries originating from the aortic arch. It is called temporal arteritis too, because of frequ...
Enhanced susceptibility of amyl nitrite or butyl nitrite induced oxidation of oxyhemoglobin into methemoglobin in the Type 2 diabetics blood compared to normal blood in independent studies was confirmed (P<0.05). For amyl nitri...
In the present study, the potential of the raw (RS) and NaOH-Modified Rice Straw (MRS) to remove copper (II) from aqueous solutions was investigated by batch tests under different experimental conditions. The chemical and mor...
Pulmonary Arterial Hypertension (PAH) is a heterogenic group of devastating disorders that characterizes higher rates of mortality and morbidity worldwide. Recent clinical studies have shown that clinical features, hemodynamic par...
Crimean War, 1853-1856. Recently, a mass grave has been exhumed which contained the bodies of numerous French soldiers who had died during the confrontation. An archaeological mission was immediately launched. As fa...
Objective: To review cranial nerve palsy as the most common presentation of neuro-ophthalmic conditions presenting to Ophthalmology Clinic, Hospital Universiti Sains Malaysia, Kelantan. Methods: Retrospective...
60 year old male patient was admitted with acute on chronic mesenteric ischeamia. He was found to have rare anatomical variant of common celiacomesenteric trunk which had atherosclerotic occlusive disease. Revascula...
Reports on the metal-toxicity are extensive; however, literature is scarce on the role of sustainable stress-mitigation approaches in this context. This work investigated the significance of growth regulator 24-epibrassinolide (24...
Rotavirus infection is a serious gastrointestinal infection that is usually prevalent during winter months and often seen in infants and young children. Studies on genotypes of prevalent rotavirus strains are quite important ...
Building information modeling (BIM), it means a digital simulation of buildings with real information. Information connotation of just geometry description also contains a large number of non-geometric properties of informati...
Vistafin is insulin-mimicking adipocytokine secreted from visceral adipose tissue, which plays an essential role in a number of biological processes affected glucose uptake regulation, inflammation, immunity, insulin resistance, v...
Purpose: Recently, a multimodal strategy using various medications and non-pharmacological methods has been recommended for treating Postoperative Nausea and Vomiting (PONV). Cold water gargling may be helpful as on...
Currently, the security of large civil engineering structures more and more people's attention, health monitoring study civil engineering at home and abroad is one of the hot topics of research. After a hundred years of research, ...
Niemann-Pick C1-Like 1 (NPC1L1) is expressed in human liver, but its mechanism of action and how it is regulated in this tissue is not well-understood. Herein, we decided to examine the effects of the inhibitor of NPC1L1, ez...
The land resources are an important resource for human survival; rational planning of land resources is conducive to the rational allocation and use of resources, promoting social and economic stability growth. Traditional la...
Our objectives in this study are to determine the prevalence of visual acuity disorders and to identify the important risk factors that associated with visual acuity disorders among Intermediate school students in Riyadh, 201...
Background: The diagnosis of Giardia spp. may pose a challenge on routine Haematoxylin and Eosin (H&E) sections of small intestinal biopsy specimens. Additionally, clinicians may not order additional laboratory ...
We report a 3-year-old Chinese girl who presented with an 18-month history of a localized asymptomatic triangular area of hair loss in the right frontotemporal area. There was no history of trauma. The parents were non consanguino...
We present a preliminary design and experimental results of phase discontinuity relaxation method for Magnetic Resonance Imaging (MRI) phase images that utilizes wavelet transform algorithm with symmetrization technique. The metho...
The SpondyloArthritidies (SpA) are a group of chronic inflammatory diseases characterized by sacroiliitis, spondylitis, enthesitis, arthritis and dactylitis. They have a strong genetic back ground especially HLA-B27 positivit...
High Low Density Lipoprotein (LDL) cholesterol levels are well-known to cause atherosclerotic diseases. The hepatic LDL receptor is the major determinant of plasma LDL-cholesterol levels, and as a result, a greater understand...
A polypoid, or submucosal tumor-like, presentation of Mucosa-Associated Lymphoid Tissue (MALT) lymphoma is relatively rare, while correct clinical and histopathological diagnoses of such cases are important for patients in order t...
The objective of the paper is to gain a deeper understanding of the levitating behavior of the disc type ultrasonic stator for possible application on moving object. For the purpose, some axial vibration measurement...
Introduction: It is estimated that adults experience between two and four colds per year and catch roughly double this number. Colds and flus are self-limiting conditions; however, there are a number of treatments to hel...
Aim: The aim of the present study was to compare the dental caries status of the 15 year old children of the southeast region of Macedonia and Bandipora District of Kashmir Division of Jammu and Kashmir State of Ind...
Cardiotoxicity due to tumoricidal drug use is defined as an asymptomatic reduction in Left Ventricular (LV) Ejection Fraction (EF) of ≥10% to <55% or as a reduction of the LVEF of ≥5% to <55% with symptoms of Hear...
Design of two-wheeled ultrasonic wheel is proposed for applications in micro-stepping displacement devices. The ultrasonic wheel includes a beam and two displacement members which are respectively pivoted on the beam. Two displace...
Stroke is the second leading cause of death and permanent disability in adults worldwide. The treatment options for ischemic are very limited and new therapies are still required. Arginase is an endogenous competitor of Nitri...
A 65-year-old male presented in the outpatient department with multiple painful ulcers and pustules on the whole trunk. The total duration of disease was 14-months. He was provisionally diagnosed as a case of pyoderma gangren...
Doxorubicin (DOX) is a potent anticancer drug whose application is hampered by its cardiotoxicity mediated by oxidative stress and inflammation. Glycyrrhizic acid (glycyrrhizin) is a natural compound that exerts anti-inflamm...
Zingiber officinale (Z. officinale) is a perennial herb with several medicinal properties. Development of modern drugs from Z. officinale can be emphasized for the control of various diseases. The feasibility of usi...
Background: Recently developed strategies (valve repair, homograft implantation) may improve clinical outcome in surgical treatment of infective endocarditis. Careful TEE examination may allow to choice the proper surgical treatme...
Kawasaki disease is a systemic vasculitis of unknown etiology. It usually affects small and medium-sized vessels. The complication of coronary artery is aneurysm, which may lead to myocardial ischemia and infarction due to st...
We report the use of dabigatran was found to be associated with Factor VIII inhibitors and prolonged APTT in the three cases. Taking the dabigatran was recognized prolonged APTT, low titer Factor Ⅷ inhibitors and reduction ...
Introduction Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is a common human enzyme deficiency. Molecular abnormalities data from Egypt are scarce, and have not been extensively investigated. To fill this...
Background: Pregnant women are more susceptible to periodontal disease and it may be associated with adverse pregnancy outcomes. Objectives: The objectives of this study were to assess women’s knowledge...
Malignant hypertension is an uncommon cause of serous macula detachment. We report a case of a 27-year-old gentleman who presented with unilateral macula detachment. His blood pressure was increased during presentation. His renal ...
Background: Previous studies demonstrated visceral adiposity in relation to metabolic disorder may mediate systemic inflammation and predict cardiovascular outcomes. However, data regarding visceral adipose tissue b...
Amyotrophic Lateral Sclerosis (ALS) is a debilitating neurodegenerative and neurovascular disorder with multi-factorial molecular mechanisms of pathology. At the very core of B-CNS B alterations associated with ALS are the ke...
The association between Schistosomes infection and autoimmunity has been studied extensively in the medical literature. Schistosomiasis might induce autoimmune activity by several mechanisms: molecular mimicry, production of ...
For oral health, it is an important issue to keep and, if deteriorated, to improve salivary secretion. Although mechanical stimulation in chewing and masticating bolus induces the salivary secretion, it is not ...
Rapid resistance to mupirocin occurs among strains of Methicillin-Resistant Staphylococcus Aureus (MRSA) which the main etiological agent is causing community-acquired and hospital-acquired infections. Powdered samples of Sr-doped...
Aim: The aim of this study was to investigate the relationship between Body Mass Index (BMI) and mean DMFT score of 12 year old school children in Ohrid city. Materials and Methods: This cross-sectional study asse...
A number of parasitic diseases have been reported to be transmitted by blood transfusion, including malaria, leishmaniasis, Chagas' disease, babesiosis, toxoplasmosis and filariasis. Majority of blood banks do not s...
The purpose of this work was to report a clinical case of a spayed, 13-year-old diabetic poodle on insulin therapy with insulin resistance and poor diabetes control secondary to severe periodontitis. Prior to establ...
Purpose: To describe a new subtype of retinal tumor. Conclusion: To the authors’ knowledge, we report a case of benign retinal tumor not previously described, that seemed a vasoproliferative tumor but with unusual histo...
A number of parasitic diseases have been reported to be transmitted by blood transfusion, including malaria, leishmaniasis, Chagas' disease, babesiosis, toxoplasmosis and filariasis. Majority of blood banks do not screen donor blo...
Finger millet, is a highly self-pollinated, allo-tetraploid crop believed to have been domesticated in East Africa, probably in the highland region that extends from Ethiopia to Uganda. It is known to save the lives of poor f...
Aim: The second Diabetes Attitudes, Wishes and Needs (DAWN2) study aimed to describe the psychosocial challenges faced by People With Diabetes (PWD), their families, and the Healthcare Professionals (HCPs); and to explore new aven...
Aim: To explore the psychosocial impacts, needs and wishes of Canadian Family Members (FMs) of People With Diabetes (PWD), as part of the second global Diabetes Attitudes, Wishes and Needs (DAWN2™) study. &nbs...
We report on two homeless, HIV-infected patients with intravenous drug abuse developing a generalized rash composed of angiomatous papules. Based on the clinical manifestations, routine histology and sequencing of bacterial 16S rR...
CytoMegaloVirus (CMV) is an enveloped double stranded DNA virus that belongs to Herpesviridae family. Most of the CMV infections during pregnancy are asymptomatic; but cause congenital malformations in fetus. The characteristic fe...
The study aim was to evaluate whether the Mineralocorticoid Receptors (MR) antagonist eplerenone, effects circulating microparticles originated from apoptotic and activated endothelial cells (EMP) in Chronic Heart&n...
Tinea pedis, also known as "athlete foot", refers to a superficial fungal infection of the feet caused predominately by dermatophytes. Tinea pedis is most often caused by Trichphyton rubrum and T. interdigitale. It is estimated th...
Digital mucous cysts are benign, cystic lesions of the digits typically located near the distal interphalangeal joints or near the proximal nail folds. The peak incidence rates are in the age group between 40 and 70 years. The mal...
This study demonstrates that prolonged exposure of drongos to repetitive auditory stimuli causes sustained increased levels of hypertension, which may explain observations in the local habitat.
The long-term fertility experiments is an important management strategy for monitors the changes of yield productivity and nutrient use efficiencies and will help to evaluate the sustainability of cropping pattern as well as soil ...
Background: Eating Disorders (ED) are widespread, disabling and often chronic psychiatric conditions. Currently, there is a need for further pharmacological treatment strategies. The objective of this report is to a...
Epidemiological studies have clearly indicated diabetes as a risk factor for cancer initiation and progression. Both diabetes and cancer are influenced by multiple factors of known and unknown origin. The magnitude to which these ...
The Olive Mill Wastewater (OMW) is the principal industry residue extraction of olive oil. Generally is characterized by very high organic load, due to high levels of phenolic compounds and sugars, and have minimum levels of nitro...
Obstructive Sleep Apnea (OSA) is associated with accelerated atherosclerosis, cardiovascular and cerebrovascular disease. Carotid artery Intima-Medial Thickness (CIMT) measurement has recently evolved as an important non-invasive ...
Patient with Tetralogy of Fallot (TOF) may sometimes present for noncardiac surgery. These patients may have lots of other congenital anomalies, which may need repeated surgeries for their correction. Anaesthetic management in thi...
Anaesthetic management of patients with ischaemic heart disease for noncardiac surgery can be associated with many cardiovascular complications. Sublingual isosorbide dinitrate remains one of the mainstays of management in patient...
A major objective of dental care is extending the life span of the dentition either by prevention or by treatment of dental diseases. One of the challenges in for dental professionals in their clinics is the managem...
Introduction: Sometimes, in cases of ocular trauma, the ophthalmologist must provide forensic evidence showing the status of the victim, and this requires a detailed eye examination, including an accurate description of lesio...
An 83-year-old female patient recovered from her primary Clostridium difficile-associated colitis upon antibiotic treatment and the suspension of her regular Proton Pump Inhibitor (PPI) therapy, and had a recurrence of the infecti...
A 60-year-old lady presented with a fleshy mass at the nasal limbus of the right eye of two months’ duration which was progressively increase in size. Right eye examinations showed a fleshy exophytic mass arising from infero...
Purpose: The aim of our study was to compare the level of Endothelin 1 in plasma and vitreous between type 1 and type 2 diabetes mellitus and control group and understand its role in diabetic retinopathy. Des...
Purpose: Senile cataract and cognitive dysfunction (senile dementia, cognitive impairment and Alzheimer disease) are commonly coexisting. Some ophthalmologists believe that cataract surgery not only can restore h...
Background: The aim of this study is to evaluate the use of carbamazepine as primary definitive diagnostic aid in patients with classical/idiopathic and symptomatic/ pathological trigeminal neuralgia by analyzing the pain relief. ...
Aim: To describe visual potential, etiologies, and associated ocular and neurological deficits in children with Cerebral Visual Impairment (CVI) in suburban area in Malaysia, and to discuss the clinical profiles in ...
Strabismus is a deviation of the eyes, when both eyes simultaneously cannot be directed at the object which is observed [1]. Strabismus occurs in about 2% of children under 3 years old and about 3% of all children [3]. This study ...
Background: Community acquired Acute Kidney Injury (AKI) is more common in developing countries as compared to developed countries. Understanding of the epidemiology of community acquired AKI and its outcome wi...
Introduction : Renal involvement in brucellosis in the form of acute kidney injury is rare, but interstitial nephritis, pyelonephritis, exudative glomerulonephritis, mixed cryoglobulinemia, and IgA nephropathy ...
It is now widely recognized that retrotransposons such as Long Interspersed Element-1 (LINE1 or L1s) have played an instrumental role in shaping the structure and function of our genomes. L1s contribute to ~17% of total human geno...
The rising pollution of water bodies goes along with an increase of cyanobacteria in the micro biotic community. The ability of cyanobacteria to produce toxins is well known and many cases of poisoning of animals and humans have b...
A seven year old Hispanic girl developed headache, backache and vomiting. A computed tomography showed 2 intracranial masses. A complete blood count was normal. Bone marrow aspiration showed hypoplastic but otherwise normal marrow...
Saffron, Crocus Sativus L. is a perennial bulbous herb. The plant has been priced since antiquity for its yellow orange coloured tripartite stigmas that constitute the Saffron. Also known as saffron crocus, the odour of saffron is...
Lead was a key component in the medical sciences during its early days. Over the years the toxic effects of lead has been studied in detail and have been withdrawn from the modern drugs. However lead ingestion ...
Introduction: Transcutaneous Electrical Nerve Stimulation (TENS) has been shown to be successful in treating acute as well as chronic pain. But, it has been greatly underused especially for acute pain. Cur...
We examined the stimulatory effects of lubiprostone, a bicyclic fatty acid derived from prostaglandin E1 and a Chloride Channel type-2 opener (ClC-2), on HCO3- secretion in the rat stomach and duodenum, with a focus on the EP...
Eyelid Myoclonia with Absences (EMA) can often be clinically mistaken for a tic disorder. This case report describes a 4-year-old female who presented with eye fluttering and blinking accompanied by a hand gesture described as a &...
Bacteria are ubiquitous in nature and have the ability to survive in severe conditions of low temperature, high pressure and often changing osmotic environment. However, mechanisms of survival of bacteria in extreme environments a...
Purpose: To determine the frequency of tooth loss of individuals who lived during the nineteenth century and compare it to the current prevalence of tooth loss of an adult population in the US. Materials and ...
Background: The aim of this study was to determine the perceptions and acceptability of male circumcision among the young, as well as older men and women in South Africa. Methods: A total of eleven (11) focus...
Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disease predominantly affecting women of childbearing age. Pregnancy in women with SLE is associated with higher fetal and maternal risk compared with the general populat...
Studies indicate that women with HIV infection in the United States are inadequately screened for cervical dysplasia. However, few of these studies have included women in the southern United States, where HIV incidence...
In this review, randomized controlled trials of behavioral interventions for reducing the risk of HIV in occupational settings, were systematically identified through electronic and hand searches, they were then cla...
Background and Purpose: Herpes Simplex Encephalitis (HSE), the most common cause of sporadic viral encephalitis, causes permanent neurologic deficits and disablement in many affected individuals. To our knowledge, there have been ...
Approved pharmacological preparations for the treatment of Attention Deficit Hyperactive Disorder (ADHD) are not readily available in most low and middle-income countries. There is a growing body of alternative non-pharmacolo...
T. whipplei, the causative agent of classic Whipple´s disease, also produces acute, sub-acute and chronic localized forms of infection such as endocarditis. Blood culture of patients with T. whipplei endocarditis used to be ...
Diabetes Mellitus (DM) is a condition in which a person has a high blood sugar level over a prolonged period. DM arises as a result of complete or relative insufficiency of insulin secretion and/or insulin action. There are three ...
Objective: The purpose of this study was to determine if psychological adaptation between cancer patients and their families is dependent on effectiveness of their communication related to ...
Aim: Potassium inwardly rectifying channel, subfamily J, member 11 (KCNJ11) gene has a key role in insulin secretion and is of substantial interest as a candidate gene for Type 2 Diabetes (T2D). The current work was...
Purpose: To compare infant and family demographics and weaning and discharge outcomes of infants with Neonatal Abstinence Syndrome (NAS) treated with morphine only versus treatment with morphine and phenobarbit...
Background: 5-α-ReDuctase (5ARD) deficiency, is an autosomal recessive diseases, resulting in the inability to produce the physiologically active DiHydro Testosterone (DHT) which is required for normal viriliz...
Dengue is an important mosquito borne viral infection. The classical presentation of dengue is acute febrile illness with hemorrhagic complication. Focusing on oral manifestation, it is not common. In this brief&nbs...
Early diagnosis in oral cancer may have a major role in improving survival rates, allowing patients to take advantage of less aggressive treatments, mitigating the morbidity of the process. Definitive diagnosis of oral cancer is t...
The circadian rhythm is a complex biologic phenomenon in which environmental light is a major exogenous regulator. Cataract patients’ optical system precludes optimal transmission of light, especially the shorter wavelengths...
We presented a four-year-old girl with Tay-Sachs disease who had thrombus in the right atrium. The patient was admitted to hospital with cardiopulmonary arrest and aspiration pneumonia was diagnosed. Intracardiac th...
Background: Intermittent states of hyperglycemia have been identified as risk factor for vascular complications of type 2 diabetes mellitus independent from the mean blood glucose level. 1,5-Anhydroglucitol (1,5-AG) levels de...
Background: It has been evident that there is a sharp decline in participation in physical activity for adolescent girls. Using social cognitive theory as a theoretical framework, this study was designed to examine ...
Objective: To investigate the current approach of Australia and New Zealand paediatricians to children with gastrooesophageal reflux symptoms, comparing practice against the NASPGHAN-ESPGHAN guideline. Method: Prospect...
Diet-Induced Obesity (DIO) is a major risk factor for a number of disorders including non-insulin dependent Type 2 Diabetes Mellitus (T2D). In our novel mouse model, the gene Atp10c is a strong candidate for metabolic disorders of...
Background: Testicular cancer (TC) is the most common form of cancer among men. Lack of knowledge of male cancers is a major contributor to delays in seeking care for cancer symptoms and prevention of TC. The focus ...
Background: Nitrous oxide is decreasingly used due to theoretically considered complications. However, we have not had clinically obvious complications for many decades. The present study was done to investigate&nbs...
Several earlier reports have described life – threatening airway obstruction during arthroscopic shoulder surgery performed under regional anesthesia, caused by the leakage of irrigation fluid out of the shoulder joint space...
The striking efficiency of enzyme catalysis has inspired many organic chemists to explore enzyme mechanism(s) by studying certain intramolecular processes (enzyme models) which proceed faster than their intermolecular counterparts...
There are many causes for oral malodour, and tongue coating, periodontitis, deep caries and unfitted restorations are main causes of bad breath odour. It is not difficult to reduce oral malodour by careful examination and proper t...
Objective to study the effect of doxorubicin interventional chemotherapy on rabbit VX2 renal transplantation carcinoma and its mechanism. Methods Thirty healthy New Zealand white rabbits were chosen to establish VX2 renal transpla...
Aorto-Esophageal fistula is a rare condition, causes excessive bleeding from the upper gastrointestinal tract and is associated with a high mortality. This case report demonstrates the presentation of a 63-year old female with a p...
A – 19 year – old men was reffered to our Surgical department with a 4 – month history of an asymptomatic swelling in the left supraclavicular fossa. The patient a few months ago, carried sacks of ...
In a sample of 8th and 11th grade children at one rural school located in Oregon, USA we demonstrate that measured anthropometric values are needed for accurate surveillance of body mass index (BMI). Gender and grade adjusted quan...
The anti microbial activities of three commonly used disinfectants Septol, Dettol and Z-germicides against Escherichia coli, Staphylococcus aureus and Candida albicans were investigated. Their efficacies were determined using the ...
Recent research has shown that there is a link between metabolic diseases (like diabetes, obesity and cardiovascular diseases) and bacterial population in the gut. The results of such studies indicate that Type 2&nb...
Introduction: The quest for treatment of insomnia without side effects has been elusive and thus has led to herbal therapies. Two such supplements are Ayurvedic-based herbs, Ashwagandha and valerian. Even though the...
Systemic Lupus Erythematosus (SLE) is an autoimmune disease that predominantly affects women and is characterized by widespread immunologic abnormalities. The disease involves multiple organs including the skin, joints, and kidney...
The treatment of Toxoplasma gondii (T. gondii) infection accentuates the problem of the limited effectiveness of the available anti-parasitic agents and their side effects and also, the potential appearance of resistant Toxop...
The appearance of mast cells at eruption sites was examined in acute (ACLE) and chronic (CCLE) cutaneous Lupus Erythematosus (LE). As shown by toluidine blue staining and c-kit immunostaining, mast cells were signif...
We report on a 42 year old, heterosexual black man presenting with an anal ulceration and generalized itch. Upon inspection, hyper pigmented disseminated cutaneous patches, non-removable whitish parallel plaques on the lateral bor...
Invasive listeriosis with brain infection remains a diagnostic challenge with an early treatment need to reduce morbidity and mortality. Not only is a foodborne pathogen with a rising incidence but also responsible for variable cl...
Background: Food contamination may occur at any point during its journey through production, processing, distribution, and preparation. The risk of food getting contaminated depends largely on the health status of t...
Diabetes mellitus is major independent risk factor for cardiovascular morbidity and mortality worldwide. The endothelium is crucial for preserving endothelial integrity and preventing the development of DM-related vascular injury ...
Objectives: Diabetes can affect bone via obesity, hyperglycemia, hyperinsulinemia, and hypoinsulinemia. Osteocalcin (OC) is a non-collagenous protein of the bone that contributes to bone formation. A population-base...
Cetyltrimethylammonium Bromide (CTAB) and Dodecyl Trimethyl Ammonium Bromide (DTAB) were used to non-covalently functionalize Multi-Walled Carbon Nanotubes’ (MWCNTs’) surfaces. Transmission ele...
Background: There is a significant co-morbidity between dermatological disorders and psychiatric. It has been estimated that in at least one-third of patients with skin diseases, their effective management involves&...
Aim: To estimate the prevalence of Chronic Kidney Disease (CKD) and albuminuria and its associations to prevalent cardiovascular co-morbidities in patients with type 2 diabetes in a primary care setting in Sweden. Patients a...
Elevated blood cholesterol levels are associated with the development of heart disease. Group B soyasaponins have been suggested as a factor capable of decreasing plasma lipid concentrations. Soyasaponins are naturally occurring t...
Development of Heart Failure (HF) associates with endothelial dysfunction that considered a key cause for tissue injury, and target organ damage. Endothelial Microparticles (EMPs) are small membrane vesicles that originate from ac...
Cerebral infarction in the inflammatory bowel disease was rarely reported, especially in Crohn’s disease. In this article, we report a 38-year-old male with Crohn’s disease subsequently developed cerebra...
Aim: The aim of this exploratory study within an RCT design was to examine the factors with influence on the change in the child’s glycemic control from the onset of Type 1 Diabetes Mellitus (T1DM) to 1-year post diagnosis b...
Background: BK virus (BKV) infection in renal transplant patients is a constant concern. As BK-induced nephritis may lead to graft failure, detection of the virus is of significant clinical importance. While the dia...
DNA recombinases are used to manipulate the genomic structure and to control the genetic expression in all living organisms. Cre is a P1 bacteriophage-derived tyrosine recombinase mediating the site-specific recombination between ...
Amyloidosis refers to a group of widely diverse conditions characterized by the deposition of insoluble protein within the extracellular space, leading to disruption of normal organ function. AL primary amyloidosis is associated w...
AC-11 is an aqueous extract of the botanical, Uncaria tomentosa, which has a variety of effects that enhance DNA repair and down regulate inflammation. AC-11 is essentially free of oxindole alkaloids (< 0.05%, w/w) but contains...
Objective: To evaluate the healthcare and societal economic burden of adjunctively-treated patients with uncontrolled epilepsy. Methods: A retrospective claims database (representative of the commercially insured ...
Rice (Oryza sativa L.) yield productivity over time under fixed management condition is a severe concern for countries like Bangladesh, where rice is the staple food for the human being. Long term fertilization experiment was cond...
Background: The use of antiretroviral treatment containing Zidovudine in HIV infected patients is associated with hematological toxicity to varying degrees of cytopenia particularly megaloblastic anemia. However, there is scarcity...
Aim: We hypothesized that sex differences relative to the pro-inflammatory and endothelial markers may exist and play a role in the higher CVD mortality of women with End-Stage Renal Disease and Type 2 Diabetes Mell...
Little is known regarding rates of fearing hypoglycemia and predictive factors in Japan. The aim of the study was to investigate the prevalence of a fear of hypoglycemia and predictive factors in patients with Type 1 Diabetes Mell...
A growing body of evidence supports the efficacy of exercise training in the management of lung cancer. Home-based telerehabilitation may be a favourable model; however limited information is available about te...
Obstructive Sleep Apnoea (OSA) is a sleep related breathing disorder affecting a significant section of middle aged population. The pro inflammatory state that exists in OSA patients contributes to accelerated atherosclerosis and ...
Cissampelos sympodialis (Cs) is an herb used for the treatment of several diseases due to its anti-inflammatory properties. The present study investigated the effect of oral administration of Cs extract on STZ-induced diabete...
Autoimmune Pancreatitis (AIP) is a pancreatic inflammatory disease caused by an autoimmune mechanism. Histologically, two subtypes exist: type 1 characterized by lymphoplasmacytic sclerosing pancreatitis and ty...
Introduction Intravascular large B-cell lymphoma is a rare subtype of diffuse large B-cell lymphoma with an estimated frequency of less than one percent of all lymphomas. It has a variety of presentations and i...
Objective: To know assistance functions performed in primary and hospital care for patients with HIV disease. Design: Retrospective Participants: 167 cases with HIV disease assigned to three health ...
Prostate cancer (PCa) is one of the most common malignant diseases in western world and now emerging as a challenging disease in developing countries. Although much progress has been done to control of androgen sensitive PCa in re...
Reiki is believed to be an ancient healing practice that originated thousands of years ago. Reiki therapy has no side effects and thought to provide harmony and balance to improve physical, emotional, mental, and sp...
Catheter-Associated Urinary Tract Infection (CAUTI) is common worldwide health care associated problem. Antibiotic resistance in CAUTI is due to wide spread use of urinary catheter and inappropriate use of antibiotics. The present...
Nano suspensions have gained great interest in the last decade as a formulation tool for poorly soluble drugs. By decreasing particle sizes nano suspensions enhance dissolution rate and bioavailability of the drug. Recently, nanos...
We report a 7-month-old female infant with Miller Fisher Syndrome (MFS), presenting with external ophthalmoplegia, blepharoptosis, ataxia, and loss of deep tendon reflexes. We treated the patient with high-dose immunoglobulin ther...
A 63 year-old woman with a cirrhosis due to chronic hepatitis B infection was admitted to our hospital with massive tarry stool. Endoscopy revealed bleeding duodenal vascular ectasia in the posterior wall of the second portion. We...
Purpose: Laparoscopic sleeve gastrectomy has proven effectiveness regarding weight reduction, but metabolic consequences, especially in the long-term, have not yet been adequately clarified. The aim of the present study is to...
Disseminated tuberculosis to the brain and spine may present before typical tuberculosis systemic symptoms manifest. We present a case where a patient presented with progressive paraplegia and change in mental statu...
Controlled drug delivery system is to make sure safety and to improve effectiveness of the drugs as well as patient compliance. A controlled release system includes any delivery system that achieves slow release of the drug over a...
Anti-A and anti-B haemolysins are lytic antibodies that cause haemolysis of red blood cells of recipients when ‘O’ group blood or plasma is transfused to non ‘O’ group patients. They are known to cross the ...
Comparative studies between sodium nitrite and isoamyl nitrite in nitrite induced methemoglobin formation of diabetic’s blood have been undertaken. First the effect of sodium nitrite on human Type 2 diabetics’ blo...
In the field of medicine, the acquisition of communication skills is essential for an effective, complete and personalized treatment. This is particularly true for delicate fields such as incurable diseases, palliative care (PC) a...
Studies have shown great physical and emotional vulnerability among informal family caregivers of dying cancer patients as a result of the demanding care they provide. However, many informal family caregivers find it difficult to ...
Diabetes Mellitus (DM) is a chronic metabolic disease with complicated complex pathogenesis. Frequency of newly DM arises worldwide and associated with steadily increased morbidity and mortality due to DM-related co...
Introduction: Overweight and obesity is growing drastically worldwide, with increasing portion sizes of processed food identified as one of the contributing factors. To date there has been no research looking at the repo...
Impaired Awareness of Hypoglycemia (IAH) is associated with Severe Hypoglycemia (SH). This study investigated the actual state of hypoglycemia, including IAH, in patients with Type 2 Diabetes. A questionnaire survey on hypoglycemi...
Introduction Advanced techniques of radiotherapy have decreased the late complication rate to < 1% at the larynx. Cartilage necrosis is one of rare toxicities associated with radiotherapy. Case presentation We present the ...
We describe two cases of moyamoya disease associated with headache which had been diagnosed as migraine with aura meeting the International Headache Society criteria. Administration of triptan was clinically effective. Initial com...
Hepatitis A virus (HAV) is transmitted by the fecal-oral route, and the epidemiology of HAV is associated with hygiene and socioeconomic status. In this study, we investigated the seropositivity for HAV and the associated soc...
Sustained Release Drug Delivery System (SRDDS) is designed to release a drug at a predetermined rate by maintaining a constant drug level for a specific period of time with minimum side effects. Now a day’s focus on the...
We previously reported that the largest p150 subunit of chromatin assembly factor 1 (p150CAF1), which promotes chromatin assembly in the context of DNA replication, interacts directly and preferentially with small ubiquitin-relate...
In the Corynorhinus mexicanus four enzymes related to Reactive Oxygen Species (ROS) modulation are present in the cephalic and caudal region of the epididymides during the progress of the epididymis sperms and their maturatio...
Metabolic Syndrome (MS) can be diagnosed from the age of 10 years, when the coexistence of abdominal obesity, glucose metabolism disorders, dyslipidemia, and hypertension is observed. A binding part of MS is insulin resistanc...
Tinea capitis favosa, also termed favus, is a chronic inflammatory dermatophyte infection of the scalp usually caused by Trichophyton schoenleinii. It can be acquired during childhood or adolescence and typically persists into adu...
Aim: To evaluate the antiemetic efficacy and safety of olanzapine in Japanese women with nausea and/or vomiting refractory to the standard antiemetic regimen. Methods: We retrospectively reviewed the medical recor...
The Ethernet must work. In this paper, we confirm the improvement of e-commerce. WEKAU, our new methodology for forward-error correction, is the solution to all of these challenges.
Protozoan parasites cause serious human and zoonotic infections, including life-threatening diseases such as malaria, African and American trypanosomiasis and Leishmaniasis. According to World health organization evaluation, these...
Owing to numerous problems of controlling viral diseases many African medicinal plants have been screened for their antiviral activity. A review of studies on this shows that 58 plant species had in-vitro antiviral properties agai...
L. pneumophila is an intracellular bacterium that replicates inside a membrane-bound vacuole called Legionella Containing Vacuole (LCV), where it profusely releases its HtpB chaperonin. From LCV, HtpB reaches the host cell cytopla...
Aim and objectives: The aim of this study is to investigate the knowledge, attitudes and practices of oncology nurses towards CAM in cancer care in Qatar. Background: CAM is widely used by patients with cancer wo...
Cardiopulmonary Bypass (CPB), a non-physiological intervention that maintains the blood circulation outside the body, brings about hemodynamic and biochemical changes, but these have not been elucidated in detail. Therefore, the a...
Inborn Errors of Metabolism (IEM) are rare congenital diseases. It arises due to a defect of single genes that code for enzymes that helps to convert substrates into their products by participating in certain metabolic pathway. IE...
Pharmaceutical industries have received much interest in pharmaceutical research in the area of oral drug delivery. Oral administration of drug is the most convenient and versatile way due to the simple and comfortable use and fle...
Targeting drugs to the colon is one of the modern research areas in pharmaceutical sciences at the deciding time, place and exact amount, and improving patient flexibility, compliance and bioavailability. To reach doing well colon...
Tyrosine phosphorylation plays a critical role in cell biological functions, particularly in signal transduction. Mass spectrometry (MS)-based proteomic analysis of tyrosine-phosphorylated (pTyr) proteins remains challenging...
Objective: To study the effect of early ecological immune enhanced enteral nutrition on nutritional status and immune function and intestinal mucosal barrier of the gastrointestinal fistula patients. Methods: The 54 p...
Objective: Can Continuous Glucose Monitoring (CGM) systems predict capillary glucose levels < 0.80g/L Research Design and Methods: During their education to the use of CGMS, thirty-three patients with T...
Aim: To investigate the ethnic differences in knowledge on own diabetes disease and self management in Assyrian/Syrian-born and Swedishborn patients in Swedish town. Methods: This cross-sectional, questionnaire based s...
Endometrial Cancer (EC) is the most frequently diagnosed gynecological malignancy and the fourth most common cancer diagnosis overall among women. As with many other forms of cancer, it has been shown that certain miRNAs are ...
A pubmed hit search teaches us that Human Body Composition (BC) is a frequently used issue in nutrition publications. Body composition is a branch of human biology and is subject to variable interpretation by its users. Quant...
Biological Therapeutics (BTs) present a novel frontier for the treatment of autoimmune diseases, such as rheumatoid arthritis, psoriasis, Crohn's disease and several other conditions. BTs constitute highly selective compounds targ...
The aim: was to ascertain the frequency of self reported hypoglycemia among people with type 2 diabetes; a further aim was to determine how participants received information about hypoglycemia, if hypoglycemia led to restric...
It has long been the holy grail of cell encapsulation to treat diabetes with insulin producing cells that are shielded from rejection or clearance by the host immune system. Indeed, the idea has been around for more than 50 years ...
A 25-year-old woman presented to our hospital with a 1-week history of cough and shortness of breath. A chest radiograph showed a left-sided pleural effusion that contained chyle. The findings of other examinations...
Antimicrobial effects of the combination of cranberry and wild blueberry extracts on Escherichia coli O157:H7, Listeria monocytogenes, Salmonella typhimurium, and Staphylococcus aureus in Distilled Water (DW) and Brain Heart Infus...
Infection by Human Immunodeficiency Virus-1 (HIV-1) is modulated by the interaction of host cell, viral proteins, and environmental stimuli. Critically involved cellular factors are apolipoprotein B mRNA-editing enzyme-catalytic, ...
Aim and epidemiological Cross sectional study to determine the most common causes of congenital cataract in a sample of Iraqi patients referred to the main tertiary eye center in Iraq. Setting: Ibn Al-Haithem Teaching eye Hos...
Background: In coming years, the need for clinical research in Physical Medicine and Rehabilitation (PMR) will increase. In face of an aging population and greater emphasis on evidence-based medicine, the field must be prepared to...
A total of 152 malaria parasitaemic pregnant women of varying ages and gravidities, whose pregnancies had advanced up to the 6th months and above, were enrolled in the study. Seventy-six (76) each were randomised into supplemented...
In stroke, ninety percent of survivors have motor sequelae, being the main one is hemiplegia or hemi paresis, respectively defined as total or partial paralysis of the movements of one side of the body, interfering directly on the...
Background: Rapunzel syndrome is an extremely rare intestinal condition in humans resulting from eating hair (trichophagia) . Rapunzel syndrome presents a rare type of trichobezoar with an extension of the hair into small bow...
Introduction: Pulmunary baritosis is secondary to inhalation of barium dust with extremely dense, discrete opacities on the chest radiograph. Baritosis has been classified as a benign pneumoconiosis. We present an unusual case of ...
Building bases of scientific evidence about nitrite in humans continues to oppose the general safety in human health. Therefore, we investigate the testicular tissue inflammation caused by oral administration of sodium nitrite. Tw...
Achondroplasia is an inherited skeletal disorder affecting bone growth and development. It presents the most common cause of dwarfism in humans. Associated anatomical and physiological changes present a major challenge to ma...
Background: Despite the technological and medical advances in perinatal and neonatal care, the rate of preterm birth continues to rise and contribute to the increased costs to the health care systems worldwide. Neonatal clinicians...
Background: Although H.pylori is a human carcinogen agent, the efficacy of its eradication on gastric cancer prevention is yet to be demonstrated. Piedmont, Northwest Italy, is an area with a relatively high inciden...
Pancreatic cancer belongs to the most malignant gastrointestinal cancers and the treatment options are limited. The two bioactive components of turmeric, curcumin and turmeric oil, are reported to have anticancer properties agains...
Introduction: Dento-alveolar trauma to the maxillary incisors often requires combined clinical and radiographical follow-up. The number of radiographs can add up substantially in particular cases, which subsequently results in a h...
Urban air pollution has been one of the most important pollution problem for many decades. Airborne particulate matter (PM) from combustion sources is considered the most important air pollutants for adverse health effects to huma...
Background and Aim: Percutaneous Endoscopic Gastrostomy (PEG) provides for enteral nutrition in children with feeding problems. PEG, however, is not without complications. The present study has the aim to identify the inciden...
Objectives: Vitamin D (VD) has multiple physiological function including bone-mineral metabolism and musculo-skeletal effects. The purpose of this study is to disclose actual circumstances of VD contentment and characteristics in ...
Osteoarthritis (OA) is cartilage failure resulting in joint pain and loss of joint functions. Knee OA is the OA of knee that mechanical forces have major effect on initiation and progression of it. Knee OA is the most common ...
Systemic Lupus Erythematosus (SLE) is a typical systemic autoimmune disease characterized by the production of auto antibodies reactive to nuclear and cellular components such as double-stranded DNA, RNA-proteins and phosphol...
Crohn’s disease is an idiopathic chronic transmural inflammatory condition of the intestine. Common complications include intestinal obstruction,internal and external fistulae, and spontaneous abcess formation...
Type 2 Diabetes Mellitus (T2DM) remains a leading contributor to cardiovascular mortality worldwide. This study was conducted to investigate the pattern of circulating Endothelial Progenitor Cells (EPCs) in T2DM&nbs...
Background: We studided the etiologies of mortality in childhood Acute Lymphoblastic Leukaemia (ALL) patients at Paediatric Oncology Department of St Aliasghar Hospital. Methods: In our hospital, between years of ...
Members of the nuclear factor-kappa B (NF-kB)/Rel family, which act as transcriptional regulators, play important roles in neuronal cell death and survival. NF-kBp50 knockout (p50-KO) mice exhibit many of the features of...
Endothelial Progenitor Cells (EPCs) are recognized a circulating pool of primitive endothelial precursors of different origin from bone marrow or peripheral tissues, which express on their surface endothelial markers, i.e. CD...
Within past decade substantial progress has been made in our understanding of the molecular mechanisms by which low intense inflammation might induce metabolic disorders, such as diabetes and metabolic syndrome. Gal-3 is low molec...
Worldwide ultimate aim of any agriculture sector or farmer is to take maximum yield. Sufficient supply of nutrients and fertilizer are not able to give maximum yield. There are numerous factors which are responsible for low yield,...