A total of 152 malaria parasitaemic pregnant
women of varying ages and gravidities, whose pregnancies
had advanced up to the 6th months and above, were
enrolled in the study. Seventy-six (76) each were
randomised into supplemented and placebo groups. Venous
blood was collected from each woman and examined for
malaria parasitaemia, using standard parasitological
techniques. Ten thousand international units of vitamin A
was administered to the supplemented group once daily for
three times per week. The placebo group also received
vitamin A soft gels devoid of its active ingredients three
times weekly. The regimen was continued as the women
were followed up until delivery of their babies. Birth
weights of the infants were determined with the use of
weighing scales, within 72 hours post-delivery. Cross
tabulations were used to calculate the percentages of low
birth weights. The mean birth weights of the infants were
analysed, using analysis of variance (ANOVA) and Fisher’s
least significance difference (FLSD), for mean separation.
T-test was used to compare birth weight in supplemented
group with those in the placebo group. Statistical
significance was established at p< 0.05. The multigravids dominated in the study. The primigravids
had the least mean age while the multigravids had the
highest. When the overall supplemented and placebo
groups were compared the placebo groups had higher
number of low birth weights that were statistically
significant (p< 0.05) among the infants of the 8th month
group women. The mean birth weights were generally
statistically higher in the supplemented group than in the
placebo group, except in a few cases with no significant
differences. Vitamin A has proved to be efficacious in
improving infant birth weights. Therefore, its
supplementation to pregnant women at safe periods and
dosages is advocated.
Keywords: Vitamin A, Supplementation, Malaria,
Pregnancy, Birthweight
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ISSN: 2378-6221
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Vitamin A Supplementation of Malaria-infected Pregnant Women and Infant Birth Weight Outcomes A Case Study of Ebonyi State, Nigeria
Elom MO1, Okafor FC 2* and Eyo JE2
Corresponding Author: Okafor FC
Received: Jul 09, 2014
Accepted: Jul 31, 2014
Published: Aug 02, 2014
Views: 3
DOI: N/A
Abstract
Okafor FC (2013), Vitamin A Supplementation of Malaria-infected Pregnant Women and Infant Birth Weight Outcomes A Case Study of
Ebonyi State, Nigeria. Gastro 2: 109.
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Copyright: © 2014 Goa. This is an open-access article distributed under the terms of the Creative Commons Attribution License, Version 3.0, which permits
unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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