Nano suspensions have gained great interest in
the last decade as a formulation tool for poorly soluble
drugs. By decreasing particle sizes nano suspensions
enhance dissolution rate and bioavailability of the drug.
Recently, nanoscale systems have received much interest
as a way to resolve solubility issues because of their cost
effectiveness and technical simplicity compared to
liposomes and other colloidal drug carriers. They have
also been used for drug targeting. Formulation of
lipophillic drugs into nano suspensions improves their
stability
and also enhances their bioavailability
significantly. Nano suspensions have unique advantages
for which they have been utilized for the production of
dosage forms suitable for administration through oral,
parenteral,
ocular
and
pulmonary routes. Nano
suspensions can be manufactured using the ‘Top Down’ or
‘Bottom’s Up’ technology and employ a variety of
components including surfactants for stability purposes
and polymers for sustained release of drug in certain
formulations. This paper reviews recent patents, methods
of preparation and marketed products with their
importance or status, novel researches and characterization
implemented till date to overcome the challenges in poorly
water soluble drugs.
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ISSN: 2378-8968
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Nano Suspension Drug Delivery System: An Overview
Sahilhusen I Jethara1, 2*, Mukesh R Patel2 and Alpesh D Patel
Corresponding Author: Sahilhusen I Jethara
Received: Sep 09, 2014
Accepted: Oct 30, 2014
Published: Nov 03, 2014
Views: 4
DOI: 10.14437
Abstract
Sahilhusen I Jethara (2014), Nano Suspension Drug Delivery System: An Overview. Aperito J Drug Design Pharmacol
1:106
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Copyright: © 2014 AJDDP. This is an open-access article distributed under the terms of the Creative Commons Attribution License, Version 3.0, which permits
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unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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