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Aperito Journal of Drug Designing and Pharmacology

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Original Research Vol. 1, Issue 2 (2015)

Nano Suspension Drug Delivery System: An Overview

Sahilhusen I Jethara1, 2*, Mukesh R Patel2 and Alpesh D Patel
Corresponding Author: Sahilhusen I Jethara
Received: Sep 09, 2014
Accepted: Oct 30, 2014
Published: Nov 03, 2014
Views: 17
DOI: 10.14437

Abstract

Nano suspensions have gained great interest in the last decade as a formulation tool for poorly soluble drugs. By decreasing particle sizes nano suspensions enhance dissolution rate and bioavailability of the drug. Recently, nanoscale systems have received much interest as a way to resolve solubility issues because of their costeffectiveness and technical simplicity compared to liposomes and other colloidal drug carriers. They have also been used for drug targeting. Formulation of lipophillic drugs into nano suspensions improves their stability and also enhances their bioavailability significantly. Nano suspensions have unique advantages for which they have been utilized for the production of dosage forms suitable for administration through oral, parenteral, ocular and pulmonary routes. Nano suspensions can be manufactured using the ‘Top Down’ or ‘Bottom’s Up’ technology and employ a variety of components including surfactants for stability purposes and polymers for sustained release of drug in certain formulations. This paper reviews recent patents,

methods  of preparation and marketed products with their importance or status, novel researches and characterization implemented till date to overcome the challenges in poorly water soluble drugs.

 

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Sahilhusen I Jethara (2014), Nano Suspension Drug Delivery System: An Overview. Aperito J Drug Design Pharmacol 1:106
Copyright: Copyright: © 2014 AJDDP. This is an open-access article distributed under the terms of the Creative Commons Attribution License, Version 3.0, which permits
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