Unilateral anemic retinopathy is an uncommon but 
reversible condition. A 43-year-old female presented with right 
eye blurring of vision for one week duration. She also had 
menorrhagia for a year. Examination showed visual acuity of 
counting fingers (right eye) and 6/6 (left eye). Right funduscopy 
showed optic disc swelling with retinal hemorrhages, cotton wool 
spots, Roth’s spots, tortuous vessels and macular edema. The left 
fundus was normal. Systemic examination revealed severe pallor 
with presence of pansystolic murmur. The uterus was enlarged. 
Her hemoglobin level was 4.7g/dl while peripheral blood film 
revealed hypochromic microcytic anemia. Other blood parameters 
and counts were normal. Blood transfusion was performed and 
she underwent a myomectomy by the gynecologist. Her vision 
improved to 6/6 and the fundus lesions resolved within three 
weeks. This case highlights the uncommon findings of unilateral 
anemic retinopathy mimicking a central vein occlusion. Workup 
for this self-limiting condition should exclude lymphoproliferative 
malignancies and coagulopathies.