We report the use of dabigatran was found to be associated with Factor VIII inhibitors and prolonged APTT in the three cases. Taking the dabigatran was recognized prolonged APTT, low titer Factor Ⅷ inhibitors and reduction of Factor Ⅷ. Once these cases stopped dabigatran in a variety of causes. At the time of dabigatran discontinuation, APTT was normal value and Factor Ⅷ, Factor Ⅷ inhibitor became the normal value. When dabigatran resumed. APTT was prolonged and low titer Factor Ⅷ inhibitors and reduction of Factor Ⅷ. Side effects of bleeding at the time of APTT prolongation was not admitted in three cases.
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ISSN: 2378-7694
Aperito Journal of Case Reports Clinical
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Original Research
Vol. 2, Issue 1 (2015)
In Three Cases, the Use of Dabigatran was Found to be Associated with Factor VIII Inhibitors and Prolonged APTT
Joji Shimono1*, Yutaka Tsutsumi1, Hiroyuki ohigashi1 and Takanori Teshima2
Corresponding Author: Joji Shimono
Received: Dec 04, 2014
Accepted: Sep 14, 2015
Published: Sep 17, 2015
Views: 11
DOI: 10.14437
Abstract
Joji Shimono (2015), In Three Cases, the Use of Dabigatran was Found to be Associated with Factor VIII Inhibitors and Prolonged APTT. Aperito J Case Rep Clin 2:108
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Copyright: © 2015 AJCRC. This is an open-access article distributed under the terms of the Creative Commons Attribution License, Version 3.0, which permits unrestricted
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