Ankylosing Spondylitis (AS) is a chronic inflammatory 
systemic disorder belonging to the SpondyloArthridies with axial 
joint involvement and enthesitis, with or without peripheral arthritis 
and systemic involvement. We know that AS has a strong genetic 
background especially HLA-B27 positivity and familial 
aggregation. HLA-B27 positivity and positive family history of AS 
and other SpondyloArthritidies can increase the chance of 
occurrence of AS. This chance in monozygot twins is more than 
dizygot and in first degree family is more than second degree. 
There are individuals who are not affected by AS currently 
but have the risk of progression towards AS in the future. This 
condition is called “Pre-Ankylosing Spondylitis state”.  
The author of this letter wants to introduce and do define 
this state by using a “Scoring system” that is delivered here. 

Keywords: Ankylosing Spondylitis, Pre-Ankylosing Spondylitis, 
Pro-Ankylosing Spondylitis