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Aperito Journal of Infectious Disease and Vaccines

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Original Research Article in Press

Prognosis with Proton Pump Inhibitor Versus H2 Blocker Therapy in Clostridium Difficile Infection

Istvan Varkonyi1*, Olena Misak1, Laszlo Kardos1, Zsolt Lampe1, Zoltan Szilvassy2 and Eva Rakoczi1
Corresponding Author: Istvan Varkonyi,
Received: Mar 24, 2015
Accepted: Apr 06, 2015
Published: Apr 09, 2015
Views: 3
DOI: 10.14437

Abstract

An 83-year-old female patient recovered from her primary 
Clostridium difficile-associated colitis upon antibiotic 
treatment and the suspension of her regular Proton Pump 
Inhibitor (PPI) therapy, and had a recurrence of the 
infection once PPI was restarted. After the treatment of 
the recurrent episode, the PPI was replaced with a 
histamine H2 receptor blocker, and she developed no more 
relapses. The switch from PPI to a H2 blocker may have 
been a recovery factor. More research is encouraged to 
clarify the extent of the suggested effect. 

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Istvan Varkonyi (2015), Prognosis with Proton Pump Inhibitor Versus H2 Blocker Therapy in Clostridium Difficile Infection. Aperito J Infect Dis Vaccines 1:106
Copyright: Copyright: © 2015 AJIDV. This is an open-access article distributed under the terms of the Creative Commons Attribution License, Version 3.0, which permits unrestricted
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