Objective: To report a case of neuro retinitis in ocular 
bartonellosis which showed good response to topical nepafenac 
0.1%, a non-steroidal anti-inflammatory drug, in addition to the 
standard treatment of systemic antibiotics. 
Result: A 14 year-old boy with history of cat scratch and fever 
prior to painless reduced vision of the left eye was clinically 
diagnosed as neuro retinitis characterized by optic disc swelling 
with subsequent development of macular star. He was started on 
topical nepafenac 0.1% which showed an improvement in visual 
acuity over 3 days. Oral azithromycin was subsequently started to 
treat the underlying cause neuro retinitis. Serologic examination 
for Bartonella henselae was positive for both immunoglobulin M 
and G.  Patient responded well to treatment with final visual 
outcome of 6/6 and serial optical coherent tomography (OCT) of 
the macula showing resolution of macular edema at one month. 
Conclusion: Usage of topical nepafenac in combination with 
systemic antibiotics appears to be beneficial and hastens the 
visual recovery of patient. Further studies are needed to 
investigate the role of topical nepafenac as an alternative to 
systemic corticosteroids in cases of neuro retinitis in ocular 
bartonellosis.