Open Access Peer Reviewed ISSN: 2378-6264

Cancer Studies

International open-access publishing for high-quality research, reviews, case studies, and scholarly communication.

Submit Manuscript
Back to Issue
Original Research Vol. 3, Issue 1 (2017)

Cause-Specific Mortality in Childhood Acute Lymphoblastic Leukemia at a Single Center in Iran

Khadijeh Arjmandi Rafsanjani, Azadeh Kiumarsi* and Leila Hashami
Corresponding Author: Azadeh Kiumarsi
Received: May 30, 2017
Accepted: Jun 25, 2017
Published: Nov 30, -0001
Views: 12
DOI: N/A

Abstract

Background: We studided the etiologies of mortality in childhood Acute Lymphoblastic Leukaemia (ALL) patients at Paediatric Oncology Department of St Aliasghar Hospital. 

Methods: In our hospital, between years of 2005 to 2012, we had 442 registered cases of ALL whose data was collected and analysed regarding to different factors including their age, sex, WBC count, immune phenotype, treatment response and timing of death and the etiologies of their mortality. 

Results: Among the new registered cases of ALL in the study period, 80 (18%) died. Infection was accountable for deaths in 58 (72.5%) cases. Septicemia, pulmonary infections were documented in 41 (51.25%), and 12 (15%) cases respectively. Eleven (13.8%) died due to haemorrhage. 

Conclusion: Infection was the chief etiology of mortality in our ALL patients. For improving survival, it is very important to advance our supportive care particularly prevention and treatment of infection. By studying mortality causes in clinical and demographic subgroups, one gains insights into development of strategies and interventions to modify treatment to decrease mortality.

 

Download PDF
Azadeh Kiumarsi et al., (2017), Cause-Specific Mortality in Childhood Acute Lymphoblastic Leukemia at a Single Center in Iran. Cancer Stud Open Access 3:116
Copyright: Copyright: © 2017 CSOA. This is an open-access article distributed under the terms of the Creative Commons Attribution License, Version 3.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Submit Manuscript Online Submission System
Indexed In
Google Scholar
DOAJ
PubMed
Scopus