Introduction 
Renal involvement in brucellosis in the form of 
acute kidney injury is rare, but interstitial nephritis, 
pyelonephritis, exudative glomerulonephritis, mixed 
cryoglobulinemia, and IgA nephropathy have been 
reported. 
Case Presentation: A teenager girl with acute kidney 
failure, oliguria, gross hematuria, hypertension, arthralgia 
and urinary abnormal sediment (proteinuria and 
hematuria) was admitted in pediatric nephrology 
department. Clinical manifestations mimicking rapidly 
progressive glomerulonephritis .She needed temporary 
hemodialysis because of symptomatic uremia. Despite 
clinical presentations, kidney biopsy findings were near 
normal with no crescent formation, no evidence of 
interstitial inflammation or glomerular involvement. 
Results of wright agglutination (a positive titer of 1/80) 
and 2 ME tests (positive titer at 1/40) in association with 
clinical presentation and prodromal symptoms (fever, 
vomiting and arthralgia) suggested acute brucella 
infection that should be confirmed by repeating the titer in 
follow up. 
Conclusion: Acute brucella infection should be 
considered in cases with acute kidney injury when 
symptoms such as arthralgia or arthritis are present 
especially in areas where brucellosis is endemic.