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Impaired Awareness of Hypoglycemia in Insulin-Treated Patients with Type 2 Diabetes

Naoki Sakane1*, Kazuhiko Kotani1,2, Kokoro Tsuzaki1, Masami Nishi1, Kaoru Takahashi1,3, Takashi Murata4, Kazunori Yamada4, Kentaro Okazaki5, Katsuyuki Yanagisawa6, Kenichi Yamada7, Nobuichi Kuribayashi8, Yasuo Totsuka9, Toru Hiyoshi10, Motoji Naka11, Masatake Sugimoto12, Yuji Aoki13, Masako Waki14, Miyuki Furuya15, Haruko Kitaoka16, Mariko Oishi17, Ikki Shimizu18, Hiroaki Miyaoka19, Akira Okada20 and Toshikazu Yamamoto21
Corresponding Author: Naoki Sakane,
Received: Oct 07, 2014
Accepted: Oct 20, 2014
Published: Oct 24, 2014
Views: 5
DOI: N/A

Abstract

Impaired Awareness of Hypoglycemia (IAH) 
is associated with Severe Hypoglycemia (SH). This 
study investigated the actual state of hypoglycemia, 
including IAH, in patients with Type 2 Diabetes. A 
questionnaire survey on hypoglycemia and patient
physician communication was conducted in 331 
patients with insulin-treated Type 2 Diabetes patients at 
16 hospitals and clinics. The rate of IAH was 22.1%. 
Glycemic control at an HbA1c level <7.0% was a 
significant risk factor of IAH (odds ratio (OR): 2.12; 
95% Confidence Interval (CI): 1.22-3.68; P =0.01), 
along with a male sex and lower body mass index. 
Concerning 
talking about hypoglycemia with 
physicians, patients with IAH showed a similar 
frequency of talking with physicians as patients without 
IAH, while patients with SH communicated more 
frequently than those without SH. Considering the 
prevalence of IAH, physicians should be conscious of 
the IAH-associated factors and talk more about 
hypoglycemia.

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Naoki Sakane (2014), Impaired Awareness of Hypoglycemia in Insulin-Treated Patients with Type 2 Diabetes. Diabetes Res Treat Open Access 1:109
Copyright: Copyright: © 2014 DRTOA. This is an open-access article distributed under the terms of the Creative Commons Attribution License, Version 3.0, which permits
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