Aperito Journal of Cellular and Molecular Biology

In vitro Isolation and Characterization of Mesenchymal Stem Cells (MSCs) from Lipoaspirate: a new Preclinical Protocol

Erika Leonardi1 and Pier Francesco Indelli2*

Mesenchymal Stem Stem Cells (MSCs) could provide alternative therapeutic solutions for a number of bone and cartilage tissue diseases, playing an important role in regenerative medicine. Several sources of...

Molecular Identification of the Most Prevalent Mutations of the Glucose-6-Posphate Dehydrogenase (G6PD) Gene in Deficient Egyptian Patients

Abeer Ramadan1*, Magda Abdel Aziz Zeidan2, Naglaa Kholoussi1, Howyda M Kamal Shaaban2, Deena Abd El Latef Elshabrawy2** and Wahiba A Zarouk1

Introduction Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is a common human enzyme deficiency. Molecular abnormalities data from Egypt are scarce, and have not been extensively investigated. To...

Effects of ezetimibe on Niemann Pick C1 Like 1 expression in human hepatocyte-like C3A cells

Catherine J Wootena, Mohammed Assisoua, DaTonye Agina and Dayami Lopez*

Niemann-Pick C1-Like 1 (NPC1L1) is expressed in human liver, but its mechanism of action and how it is regulated in this tissue is not well-understood.  Herein, we decided to examine the effects of th...

Advancing Biomarker Research for Traumatic Brain Injury (TBI)

Ron B Moyron1, 2, Richard D Catalano4, Carlos A Garberoglio4, Xian Luo-Owen4, Thomas O’Callaghan4, Nathan R Wall1, 2, 4* and David Turay1, 3, 4*

Preliminary Results of Olive Mill Wastewaters Treatment by Immobilized Microalgae

D Monteiro, B Martins and C Fernandes*

The Olive Mill Wastewater (OMW) is the principal industry residue extraction of olive oil. Generally is characterized by very high organic load, due to high levels of phenolic compounds and sugars, and hav...

Molecular Mechanisms of Cold Adaptation in Bacteria

Ashish Kumar Singh1*, Mohan Prasad Singh1 and Sisinthy Shivaji2

Bacteria are ubiquitous in nature and have the ability to survive in severe conditions of low temperature, high pressure and often changing osmotic environment. However, mechanisms of survival of bacteria ...

Zaragozic Acid A Enhances the Internalization of VLDL in Human Hepatocyte-Like C3A Cells

Soumya Ivaturi, Catherine J Wooten and Dayami Lopez*

High Low Density Lipoprotein (LDL) cholesterol levels are well-known to cause atherosclerotic diseases. The hepatic LDL receptor is the major determinant of plasma LDL-cholesterol levels, and as a result, ...

Senile Transthyretin Cardiac Amyloidosis in Patients with Plasma Cell Dyscrasias: Importance of Cardiac Biopsy for Making The Correct Diagnosis

Logan Roof1, Woodrow J. Coker2, John Lazarchick3 and Yubin Kang2, 4*

Amyloidosis refers to a group of widely diverse conditions characterized by the deposition of insoluble protein within the extracellular space, leading to disruption of normal organ function. AL primary am...

Sumo-2/3 and Rnf4 Localization to DNA Replication Foci in Cultured Human Cells Over expressing the P150 Subunit of Chromatin Assembly Factor 1

Eri Yuasa and Hisato Saitoh*

We previously reported that the largest p150 subunit of chromatin assembly factor 1 (p150CAF1), which promotes chromatin assembly in the context of DNA replication, interacts directly and preferentially wi...