Clinical Research and Development
International open-access publishing for high-quality research, reviews, case studies, and scholarly communication.
Submit ManuscriptVolume 1, Issue 2
The Association between Serum under carboxylated Osteocalcin Level and Type-2 Diabetes Mellitus: Results from the Kyushu and Okinawa Population Study
Norihiro Furusyo*1,2, Hiroaki Ikezaki2, Takeo Hayashi2, Takeshi Ihara2, Satoshi Hiramine2, Fujiko Mitsumoto2, Kazuya Ura2, Koji Takayama2, Kazuhiro Toyoda1, Eiichi Ogawa1,2, Mosaburo Kainuma1, Masayuki Murata1 and Jun Hayashi3 • 20 Dec 2014
Objectives: Diabetes can affect bone via obesity, hyperglycemia, hyperinsulinemia, and hypoinsulinemia. Osteocalcin (OC) is a non-collagenous protein of the bone that contributes to bon...
Establishing and Validation of Modified CRE/Loxp System Useful In Temporal and Spatial Control of Genetic Knocking Out Using In Vitro Approaches by Induced Alpha Complementation
Ahmed M Hamdan1, 2*, Mohammed M H Al-Gayyar3, 4 and Abdullah A Alyoussef5 • 08 Dec 2014
DNA recombinases are used to manipulate the genomic structure and to control the genetic expression in all living organisms. Cre is a P1 bacteriophage-derived tyrosine recombinase mediating the site-s...
Anaesthesia for Caesarean Section in an Achondroplastic Dwarf
Rahul Garg* and Pamela Angle • 05 Feb 2014
Achondroplasia is an inherited skeletal disorder affecting bone growth and development. It presents the most common cause of dwarfism in humans. Associated anatomical and physiological changes p...
The Diagnostic Dilemma of Intravascular Lymphoma
Lizette F Lopez1, Mahmoud Aly2, Yan H Cheng*1, 3, and Aileen Novero1 • 10 Nov 2014
Introduction Intravascular large B-cell lymphoma is a rare subtype of diffuse large B-cell lymphoma with an estimated frequency of less than one percent of all lymphomas. It has a varie...
Birth of an Online and Open Access Journal: Journal of Clinical Research and Development
Gerald Mboowa1* • 31 Oct 2014